MCPH1 Antibody - C-terminal region (ARP63864_P050)
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Product Specifications
CAS Number
9007-83-4
Gene Name
Microcephalin 1
Gene Aliases
MCT, BRIT1
Gene ID
79648
Swiss Prot
E9PH63
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MCPH1
Target
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome.
Partner Proteins
KDM1A; PHF11; TADA2A; ABCC2; E2F1; CDC27; CHD4; H2AFX; CHEK1; MDC1; TP53BP1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; SMARCA2; RAD51; NBN; MCM2; BRCA2; ATR; ATM; RPA1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
EAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLP
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
61kDa
Protein Length
562
NCBI Gene Symbol
MCPH1
Host or Source
Rabbit
Protein Name
Microcephalin Ensembl ENSP00000430768
Gene Name URL
MCPH1
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