CDC73 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

Gene Aliases

HYX, FIHP, HPTJT, HRPT1, HRPT2, C1orf28

Gene ID

79577

Swiss Prot

Q6P1J9

Accession Number

NP_078805

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish

Target

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Partner Proteins

CCDC155; FSD2; TSGA10; CEP70; VPS37B; MTUS2; UBC; TFCP2; GOLGA2; ALAS1; CIAO1; AURKB; GPRASP2; COG3; MYH14; MYL12A; ARFGEF2; NUP98; MYH9; CHUK; DNMT3B; DNMT3A; SOX2; BCL9L; PAF1; CTR9; TCF4; CTNNB1; LEO1; GTF2F1; SUV39H1; PTPN11; WDR61; HIST1H3A; RNF20; R

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KQGCQRENETLIQRRKDQMQPGGTAISVTVPYRVVDQPLKLMPQDWDRVV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

58kDa

Protein Length

531

NCBI Gene Symbol

CDC73

Host or Source

Rabbit

Protein Name

Parafibromin

Gene Name URL

CDC73

Nucleotide Accession Number

NM_024529

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