TCP1 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
T-complex 1
Gene Aliases
CCT1, CCTa, D6S230E, CCT-alpha, TCP-1-alpha
Gene ID
6950
Swiss Prot
P17987
Accession Number
NP_110379
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Target
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Partner Proteins
FUS; ERLIN2; HUWE1; CBFA2T2; UBC; TP53; NEDD1; VHL; TUBG1; SUMO2; LGALS3BP; CDC20; STAU1; INPP5K; CDC5L; VRK2; PPP4C; COPA; COPG1; USP9X; PARK2; FBXO6; YWHAQ; UBD; FBXW4; FBXO46; STK25; HDAC6; HDAC3; NPM1; ILK; CDK5; CDK2; PAN2; US3; FAM86B2; CFAP52; METT
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
HNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEA
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
61kDa
Protein Length
556
NCBI Gene Symbol
TCP1
Host or Source
Rabbit
Protein Name
T-complex protein 1 subunit alpha
Gene Name URL
TCP1
Nucleotide Accession Number
NM_030752
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