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TCP1 antibody - C-terminal region (ARP63619_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

T-complex 1

Gene Aliases

CCT1, CCTa, D6S230E, CCT-alpha, TCP-1-alpha

Gene ID

6950

Swiss Prot

P17987

Accession Number

NP_110379

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

Partner Proteins

FUS; ERLIN2; HUWE1; CBFA2T2; UBC; TP53; NEDD1; VHL; TUBG1; SUMO2; LGALS3BP; CDC20; STAU1; INPP5K; CDC5L; VRK2; PPP4C; COPA; COPG1; USP9X; PARK2; FBXO6; YWHAQ; UBD; FBXW4; FBXO46; STK25; HDAC6; HDAC3; NPM1; ILK; CDK5; CDK2; PAN2; US3; FAM86B2; CFAP52; METT

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEA

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

556

NCBI Gene Symbol

TCP1

Host or Source

Rabbit

Protein Name

T-complex protein 1 subunit alpha

Gene Name URL

TCP1

Nucleotide Accession Number

NM_030752

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