MAD1L1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Aliases

MAD1, PIG9, TP53I9, TXBP181

Gene ID

8379

Swiss Prot

Q9Y6D9

Accession Number

NP_003541

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human MAD1L1

Target

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.

Partner Proteins

CWF19L2; HAUS1; TSHZ3; CCDC94; ZSCAN32; CCHCR1; LGALSL; TRIM29; NEBL; USP15; SPATA2; BAG5; RNF8; TPM3; TPM1; PSMA1; MFAP1; TSC22D3; ALOX5; MAD2L1; TRIP13; UBC; TPR; CDC20; ZZEF1; FLNB; SIN3A; METTL21C; ZW10; MAD2L1BP; COIL; CDC27; NRD1; Cdk1; MNT; AMOTL2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQ

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

78kDa

Protein Length

718

NCBI Gene Symbol

MAD1L1

Host or Source

Rabbit

Protein Name

Mitotic spindle assembly checkpoint protein MAD1

Gene Name URL

MAD1L1

Nucleotide Accession Number

NM_003550

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