HIP1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Huntingtin interacting protein 1

Gene Aliases

SHON, HIP-I, ILWEQ, SHONbeta, SHONgamma

Gene ID

3092

Swiss Prot

O00291

Accession Number

NP_005329

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human HIP1

Target

The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.

Partner Proteins

DAZAP2; REL; HIP1; FBXO25; CLTC; BFAR; ITSN1; UBC; MAPK6; HTT; HIP1R; IFT57; PFDN1; RPS10; EIF6; CASP9; APAF1; CASP8; AP2A1; AP2B1; CASP3; CLTB; CLTA; TFAP2A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

IVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGR

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

114kDa

Protein Length

1037

NCBI Gene Symbol

HIP1

Host or Source

Rabbit

Protein Name

Huntingtin-interacting protein 1

Gene Name URL

HIP1

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