TSN Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Translin

Gene Aliases

C3PO, RCHF1, TBRBP, TRSLN, BCLF-1, REHF-1

Gene ID

7247

Swiss Prot

Q15631

Accession Number

NP_004613

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.

Partner Proteins

UBC; WDR12; NSUN2; TSNAX; TBCD; SHMT1; PPP3CA; PFDN1; NRD1; ETF1; ATP6V1C1; SETSIP; FAM129B; P3H1; ELAC2; SNX6; MYC; GIT2; TSN; EIF4A3; MAGOH; UBA6; VPS29; UCHL3; TTC4; ZBTB18; PPP1R15A; HCVgp1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

25kDa

Protein Length

228

NCBI Gene Symbol

TSN

Host or Source

Rabbit

Protein Name

Translin

Gene Name URL

TSN

Nucleotide Accession Number

NM_004622

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