DSG1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Desmoglein 1

Gene Aliases

DG1, DSG, CDHF4, EPKHE, PPKS1, SPPK1, EPKHIA

Gene ID

1828

Swiss Prot

B7Z845

Accession Number

NP_001933.2

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human DSG1

Target

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GGIGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQYS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

44kDa

Protein Length

408

NCBI Gene Symbol

DSG1

Host or Source

Rabbit

Protein Name

Desmoglein-1

Gene Name URL

DSG1

Nucleotide Accession Number

NM_001942.3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS1313531-01 0.02 mg (E-Coli)

Recombinant Pseudomonas fluorescens NADH-quinone oxidoreductase subunit I (nuoI)

Ask

View Details

MBS1313531-02 0.1 mg (E-Coli)

Recombinant Pseudomonas fluorescens NADH-quinone oxidoreductase subunit I (nuoI)

Ask

View Details

MBS1313531-03 0.02 mg (Yeast)

Recombinant Pseudomonas fluorescens NADH-quinone oxidoreductase subunit I (nuoI)

Ask

View Details

MBS1313531-04 0.1 mg (Yeast)

Recombinant Pseudomonas fluorescens NADH-quinone oxidoreductase subunit I (nuoI)

Ask

View Details

MBS1313531-05 0.02 mg (Baculovirus)

Recombinant Pseudomonas fluorescens NADH-quinone oxidoreductase subunit I (nuoI)

Ask

View Details

MBS1313531-06 0.02 mg (Mammalian-Cell)

Recombinant Pseudomonas fluorescens NADH-quinone oxidoreductase subunit I (nuoI)

Ask

View Details