ARHGEF1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Rho guanine nucleotide exchange factor (GEF) 1

Gene Aliases

LSC, GEF1, IMD62, LBCL2, SUB1.5, P115-RHOGEF

Gene ID

9138

Swiss Prot

Q92888

Accession Number

NP_945353

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGEF1

Target

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Partner Proteins

TCF4; UBC; CYFIP1; CAP2; FN1; DCUN1D1; SH3KBP1; CSNK1E; SREBF2; MEPCE; TAF10; CNKSR1; GNA13; ARHGEF1; PRKCA; CD44; RAP1A; HRAS; PIK3CA; RHOA; GNA12; ATR

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SAAVVNAIGLYMRHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPAKTKKG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

102kDa

Protein Length

912

NCBI Gene Symbol

ARHGEF1

Host or Source

Rabbit

Protein Name

Rho guanine nucleotide exchange factor 1

Gene Name URL

ARHGEF1

Nucleotide Accession Number

NM_199002

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