PIN1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Gene Aliases

DOD, UBL5

Gene ID

5300

Swiss Prot

Q13526

Accession Number

NP_006212

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish

Target

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Partner Proteins

ANKRD40; KRTAP4-2; ZMIZ2; TSC22D4; THAP7; CCDC33; CEP76; HOMEZ; ZNF446; FBXW7; CEP55; ADAMTSL4; ZBTB7B; SSBP3; NUP62; MTUS2; ARHGEF15; IKZF3; RBPMS; RAI1; CCDC184; KRTAP10-3; KRTAP10-1; KRTAP10-9; KRTAP10-7; TAB3; ZBTB9; SPERT; AMOT; PRRC1; KRT40; HEXIM2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol