AICDA Antibody

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Product Specifications

CAS Number

9007-83-4

Gene Name

Activation-induced cytidine deaminase

Gene Aliases

AID, ARP2, CDA2, HIGM2, HEL-S-284

Gene ID

57379

Swiss Prot

Q9GZX7

Accession Number

NP_065712

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence VKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFT

Target

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2) .

Partner Proteins

PGAM1; HNRNPM; KPNB1; HSPA5; FEN1; EIF2D; EEF1A1; ACTG1; ZMIZ2; HERPUD2; AICDA; CTNNBL1; RNF126; HAUS4; CPSF3; RTCB; IER5; RRM2B; XRN2; DDX19B; HNRNPA0; CCT7; DAZAP2; NUP93; RBM39; DDX21; UBE2L3; UBC; RPA1; RAD51; PPP2R1A; EXOSC6; EXOSC5; EXOSC4; EXOSC1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFT

Applications

IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

24 kDa

Protein Length

198

NCBI Gene Symbol

AICDA

Host or Source

Rabbit

Protein Name

Activation-induced cytidine deaminase

Gene Name URL

AICDA

Nucleotide Accession Number

NM_020661

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