CTSL1 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Cathepsin L1
Gene Aliases
MEP, CATL, CTSL1
Gene ID
1514
Swiss Prot
P07711
Accession Number
NP_666023
Reactivity
Human, Mouse, Rat, Sheep
Target
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
Partner Proteins
SGTA; SERPINB3; BTN3A3; RELB; PPP1CC; APOA1; ALB; UBC; EED; BAG6; GEM; ARSA; SERPINB13; CST3; CST7; CTSC; CSTB; KNG1; PLAU; TG; CD7; CSTA; RXRA; CXCL8; IGFBP3; CD74; GCG; COL18A1; CUX1; CTSL; SLPI
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVG
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 77%; Rat: 77%; Sheep: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
36kDa
Protein Length
333
NCBI Gene Symbol
CTSL
Host or Source
Rabbit
Protein Name
Cathepsin L1
Gene Name URL
CTSL
Nucleotide Accession Number
NM_145918
Curated Selection
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