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CTSL1 antibody - C-terminal region (ARP63239_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Cathepsin L1

Gene Aliases

MEP, CATL, CTSL1

Gene ID

1514

Swiss Prot

P07711

Accession Number

NP_666023

Reactivity

Human, Mouse, Rat, Sheep

Target

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Partner Proteins

SGTA; SERPINB3; BTN3A3; RELB; PPP1CC; APOA1; ALB; UBC; EED; BAG6; GEM; ARSA; SERPINB13; CST3; CST7; CTSC; CSTB; KNG1; PLAU; TG; CD7; CSTA; RXRA; CXCL8; IGFBP3; CD74; GCG; COL18A1; CUX1; CTSL; SLPI

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVG

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 77%; Rat: 77%; Sheep: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

36kDa

Protein Length

333

NCBI Gene Symbol

CTSL

Host or Source

Rabbit

Protein Name

Cathepsin L1

Gene Name URL

CTSL

Nucleotide Accession Number

NM_145918

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