IL6ST Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 6 signal transducer (gp130, oncostatin M receptor)
Gene Aliases
CD130, GP130, HIES4, CDW130, IL-6RB, sGP130
Gene ID
3572
Swiss Prot
P40189-2
Accession Number
NP_786943
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Target
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM) . This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis.
Partner Proteins
SGTB; KCNIP3; UBQLN1; UBC; MAGEA11; SOCS3; PTPN11; IL31RA; CDK9; LIF; OSMR; PIK3CG; IL6ST; CTF1; TLE1; AR; ERBB3; PRKCD; TYK2; PTPN6; PLAUR; OSM; VAV1; ERBB2; LIFR; IL6R; JAK1; IL6; HCK; CNTFR; CNTF; STAT3; SHC1; PIK3R1; JAK2; GRB2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV
Applications
WB, IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Rabbit: 77%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
35kDa
Protein Length
329
NCBI Gene Symbol
IL6ST
Host or Source
Rabbit
Protein Name
Interleukin-6 receptor subunit beta
Gene Name URL
IL6ST
Nucleotide Accession Number
NM_175767
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