DRD3 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Dopamine receptor D3

Gene Aliases

D3DR, ETM1, FET1

Gene ID

1814

Swiss Prot

P35462

Accession Number

NP_387512

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Target

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD) .

Partner Proteins

SLC9A3; USP48; EEF1G; CLIC6; MPDZ; EPB41L2; GIPC1; NCS1; EPB41L1; EEF1B2; NCK1; FLNA; GNAI1; EPB41; GRB2; RDX

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QERGGELKREEKTRNSLMPLREKKATQMVAIVLGAFIVCWLPFFLTHVLN

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 86%; Guinea Pig: 75%; Horse: 79%; Human: 100%; Pig: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

41kDa

Protein Length

367

NCBI Gene Symbol

DRD3

Host or Source

Rabbit

Protein Name

D (3) dopamine receptor

Gene Name URL

DRD3

Nucleotide Accession Number

NM_033663

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