DACT1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

Gene Aliases

DPR1, TBS2, FRODO, HDPR1, DAPPER, THYEX3, DAPPER1

Gene ID

51339

Swiss Prot

A8MYJ2

Accession Number

NP_001072988

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

Target

DACT1 positively regulates DVL2-mediated signaling pathways during development. It binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway.

Partner Proteins

BECN1; PIK3C3; ATG14; CBX6; PPP1CC; Dact1; Dact3; C7orf25; TK1; SH3GL2; CSNK2B; LEF1; HDAC1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSES

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

86kDa

Protein Length

799

NCBI Gene Symbol

DACT1

Host or Source

Rabbit

Protein Name

Dapper homolog 1

Gene Name URL

DACT1

Nucleotide Accession Number

NM_001079520

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