PLAUR Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
CD87, UPAR, URKR, U-PAR
Gene ID
5329
Swiss Prot
Q9GK80
Accession Number
NP_002650
Reactivity
Human, Mouse
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of PLAUR
Target
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Partner Proteins
TEX101; PLAU; LYN; ELAVL1; VMA21; TXNDC17; SCAF4; SDHAF2; UBQLN2; WDHD1; SELENBP1; TBCA; PSAP; CTSA; OXCT1; NOTCH2; HDLBP; CTTN; LRP1B; SURF2; SRPX2; MMP12; IL6ST; FAP; KNG1; VTN; TYK2; PFN2; JAK1; HCK; FYN; ITGB1; EEF1A1; ITGAM; LRP1; IGF2R; ITGB2; PDGFR
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
ELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVT
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 82%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
37kDa
Protein Length
335
NCBI Gene Symbol
PLAUR
Host or Source
Rabbit
Protein Name
Urokinase plasminogen activator surface receptor
Gene Name URL
PLAUR
Nucleotide Accession Number
NM_002659
Curated Selection
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