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TES Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Testis derived transcript (3 LIM domains)

Gene Aliases

TESS, TESS-2

Gene ID

26136

Swiss Prot

Q9UGI8

Accession Number

NP_056456

Reactivity

Human, Cow, Dog, Guinea Pig, Horse, Pig, Sheep

Target

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

Partner Proteins

SUMO2; VPS25; RPRD1B; OSGEP; NAGK; HNRNPUL1; EPRS; EVL; SOCS3; SPTAN1; THADA; AHCYL1; SSSCA1; ZPR1; IGBP1; ELAVL1; UBC; ARAP1; Cep350; ENAH; SPOCK2; ACTL7A; TES; ZYX; VASP; GRIPAP1; TLN1; ACTN1; RAB8B; ACTA1; GRIP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYA

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 91%; Horse: 79%; Human: 100%; Pig: 93%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

47kDa

Protein Length

421

NCBI Gene Symbol

TES

Host or Source

Rabbit

Protein Name

Testin

Gene Name URL

TES

Nucleotide Accession Number

NM_015641

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