What is the catalog number for HLA-C antibody - C-terminal region (ARP63059_P050)?

The catalog number for HLA-C antibody - C-terminal region (ARP63059_P050) is ARP63059_P050.

What sizes are available for HLA-C antibody - C-terminal region (ARP63059_P050)?

HLA-C antibody - C-terminal region (ARP63059_P050) is available in the following size(s): 100 µL.

Is HLA-C antibody - C-terminal region (ARP63059_P050) in stock?

HLA-C antibody - C-terminal region (ARP63059_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

HLA-C antibody - C-terminal region (ARP63059_P050)

Selected Variant

ARP63059_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Major histocompatibility complex, class I, C

Gene Aliases

MHC, HLAC, HLC-C, D6S204, PSORS1, HLA-JY3

Gene ID

3107

Swiss Prot

Q29960

Accession Number

NP_002108

Reactivity

Human, Pig, Rabbit

Target

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described.

Partner Proteins

UBC; RNF139; NEDD8; SUMO1; ADRB2; MMS19; YBX1; CDC25A; BATF2; PRRG4; env; TANK; FBXO6; PCK1; CXCR4; KIR2DL2; KIR2DL1; LILRB2; KIR2DL3; TAPBP; LILRB1; KIR2DS4; KIR2DS2; KIR2DS1; CD8A; TAP2; HSPA5; B2M; CALR; HLA-C

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVET

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Pig: 100%; Rabbit: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

366

NCBI Gene Symbol

HLA-C

Host or Source

Rabbit

Protein Name

HLA class I histocompatibility antigen, Cw-16 alpha chain

Gene Name URL

HLA-C

Nucleotide Accession Number

NM_002117

Price

Frequently Asked Questions

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