MCC Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Mutated in colorectal cancers

Gene Aliases

MCC1

Gene ID

4163

Swiss Prot

P23508-2

Accession Number

NP_002378

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse

Target

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

CSNK1E; ERBB2IP; CBX5; GTF2E2; APP; DYNC1I1; NEK2; NFKBIB; STRIP1; VPS35; STRN3; STRN4; SNRNP200; PDCD10; PAICS; PSME3; CCNA1; EIF3A; STK24; EZR; VHL; VDAC1; VCP; TPM3; TARS; STRN; PSMD2; PPP2R1A; PFKP; PFAS; MYH10; MTHFD1; MARS; LTA4H; KRT18; IARS; HPRT1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SSTSSGSKDKPGKECADAASPALSLAELRTTCSENELAAEFTNAIRREKK

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol