MCC Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Mutated in colorectal cancers
Gene Aliases
MCC1
Gene ID
4163
Swiss Prot
P23508-2
Accession Number
NP_002378
Reactivity
Human, Mouse, Rat, Dog, Guinea Pig, Horse
Target
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
CSNK1E; ERBB2IP; CBX5; GTF2E2; APP; DYNC1I1; NEK2; NFKBIB; STRIP1; VPS35; STRN3; STRN4; SNRNP200; PDCD10; PAICS; PSME3; CCNA1; EIF3A; STK24; EZR; VHL; VDAC1; VCP; TPM3; TARS; STRN; PSMD2; PPP2R1A; PFKP; PFAS; MYH10; MTHFD1; MARS; LTA4H; KRT18; IARS; HPRT1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SSTSSGSKDKPGKECADAASPALSLAELRTTCSENELAAEFTNAIRREKK
Applications
WB, IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 79%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
91kDa
Protein Length
829
NCBI Gene Symbol
MCC
Host or Source
Rabbit
Protein Name
Colorectal mutant cancer protein
Gene Name URL
MCC
Nucleotide Accession Number
NM_002387
Curated Selection
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