SARS2 antibody - N-terminal region (ARP62708_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Seryl-tRNA synthetase 2, mitochondrial

Gene Aliases

SYS, SARS, SERS, SARSM, SerRS, SerRSmt, mtSerRS

Gene ID

54938

Swiss Prot

Q9NP81

Accession Number

NP_060297

Reactivity

Human

Target

This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA (Ser) and participates in the biosynthesis of selenocysteinyl-tRNA (sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease.

Partner Proteins

ILF2; CDH2; CALU; PRKCDBP; NENF; MATR3; PPT2; TUFM; SPTAN1; MTHFD1; ILF3; CUL3; RAD21; UBC; ICT1; USP44; DMWD; CASP3; EEF1A1; PUF60

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

57kDa

Protein Length

518

NCBI Gene Symbol

SARS2

Host or Source

Rabbit

Protein Name

Serine--tRNA ligase, mitochondrial

Gene Name URL

SARS2

Nucleotide Accession Number

NM_017827

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