EIF3D antibody - N-terminal region (ARP62386_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Eukaryotic translation initiation factor 3, subunit D

Gene Aliases

EIF3S7, eIF3-p66, eIF3-zeta

Gene ID

8664

Swiss Prot

O15371

Accession Number

NP_003744

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.

Partner Proteins

LZTS2; BEND5; HOMER3; SAT1; TRIM27; REL; SUMO2; SUMO3; STAU1; UBC; RNF2; RPL35; RPS28; RPS27; RPS20; RPS18; RPS12; RPS11; RPS9; RPS4X; RPL23A; HNRNPU; DDX3X; EIF3L; EIF3K; EIF3H; EIF3C; EIF3A; EIF3E; gag-pol; EIF3M; EIF3J; EIF3I; EIF3G; EIF3F; EIF3B; VCAM

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

60kDa

Protein Length

548

NCBI Gene Symbol

EIF3D

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 3 subunit D

Gene Name URL

EIF3D

Nucleotide Accession Number

NM_003753

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