GADD45GIP1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Growth arrest and DNA-damage-inducible, gamma interacting protein 1

Gene Aliases

PRG6, CRIF1, PLINP, CKBBP2, Plinp1, MRP-L59, PLINP-1, CKbetaBP2

Gene ID

90480

Swiss Prot

Q8TAE8

Accession Number

NP_443082

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

Target

GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.

Partner Proteins

FBXW11; UBC; LIN28A; EXOSC4; UPF2; TMEM177; MRPL11; MRPL14; TSR1; PTRH2; EIF3C; TAP1; MRPL12; APP; COPS5; HNRNPA1; NFE2L2; ICT1; AR; IKBKG; GADD45G; GADD45B; NR4A1; GADD45A; CSNK2B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SLRVKQLAEEQKRREREQHIAECMAKMPQMIVNWQQQQRENWEKAQADKE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol