BRE antibody - C-terminal region (ARP62254_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

BRISC and BRCA1 A complex member 2

Gene Aliases

BRE, BRCC4, BRCC45

Gene ID

9577

Swiss Prot

Q9NXR7

Accession Number

NP_954664

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.

Partner Proteins

FAM175B; UBC; BABAM1; AKAP2; TFG; OPTN; HNRNPA2B1; SUMO2; PAXIP1; MDC1; BRCA1; GRB2; UBD; GFI1B; UIMC1; BRCC3; FAM175A; NCOA3; COPS5; SUMO1; TNFRSF1A; FAS; MMS19; UGGT2; TMX3; DHRS7B; FKBP8; TTC28; ATG2A; SLC25A13; LRPPRC; USP7; SSR3; SHMT2; RPN2; PHB; UB

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFVPQFQEAAFAN

Applications

WB, IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

43kDa

Protein Length

383

NCBI Gene Symbol

BABAM2

Host or Source

Rabbit

Protein Name

BRISC and BRCA1-A complex member 2

Gene Name URL

BABAM2

Nucleotide Accession Number

NM_199194

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MR217776L3 10 µg

Atg9b (NM_001002897) Mouse Tagged Lenti ORF Clone

Ask

View Details

mh30970 500 ng

LentimiRa-Off-hsa-miR-543 Vector

Ask

View Details

SR404915 1 Kit

Nmrk2 Mouse siRNA Oligo Duplex (Locus ID 69564)

Ask

View Details

45139106 1 µg

SOX17 AAV Vector (Rat) (CMV)

Ask

View Details