HOMER3 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Homer homolog 3 (Drosophila)
Gene Aliases
VESL3, HOMER-3
Gene ID
9454
Swiss Prot
Q9NSC5
Accession Number
NP_001139193
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Target
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Partner Proteins
PPP1R18; EAF1; NEBL; ABI2; POM121; HOMER1; HOMER3; USP2; EIF3D; WIPF1; SNRPF; PSMA1; PKN1; MOS; RUNX1T1; SRPK2; Grm5; Homer2; ABI3; PSMA2; APP; Pax6; IKBKB; PSMC5; Cdc16; Snw1; DYNLL2; FAT1; CEBPB; RYR1; ITPR1; TRPC5; TRPC4; TRPC1; FRYL
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
DSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGELTSPAL
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
39kDa
Protein Length
358
NCBI Gene Symbol
HOMER3
Host or Source
Rabbit
Protein Name
Homer protein homolog 3
Gene Name URL
HOMER3
Nucleotide Accession Number
NM_001145721
Curated Selection
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