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HOMER3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Homer homolog 3 (Drosophila)

Gene Aliases

VESL3, HOMER-3

Gene ID

9454

Swiss Prot

Q9NSC5

Accession Number

NP_001139193

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Target

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

Partner Proteins

PPP1R18; EAF1; NEBL; ABI2; POM121; HOMER1; HOMER3; USP2; EIF3D; WIPF1; SNRPF; PSMA1; PKN1; MOS; RUNX1T1; SRPK2; Grm5; Homer2; ABI3; PSMA2; APP; Pax6; IKBKB; PSMC5; Cdc16; Snw1; DYNLL2; FAT1; CEBPB; RYR1; ITPR1; TRPC5; TRPC4; TRPC1; FRYL

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGELTSPAL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

358

NCBI Gene Symbol

HOMER3

Host or Source

Rabbit

Protein Name

Homer protein homolog 3

Gene Name URL

HOMER3

Nucleotide Accession Number

NM_001145721

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