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PTPA Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 2 phosphatase activator

Gene Aliases

PP2A, PR53, PPP2R4

Gene ID

5524

Swiss Prot

Q15257

Accession Number

NP_821068

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

AMOT; MID1; BHLHB9; SP3; STAT1; IER3; UBC; PRKCB; MAPT; EIF4EBP1; RACGAP1; APP; CAV1; AKT1; MAP2K3; MARK2; ATM; STK26; AURKB; CYLD; PPP1CA; HHV8GK18_gp81; SP1; PPP2CA; MDM2; SET; ARRB2; PIM1; PTEN; PPP2R1A; MYOCD; MYLPF; CCT5; CCT8; CCT2; CCT4; CCT7; CCT3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWS

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

358

NCBI Gene Symbol

PTPA

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 2A activator

Gene Name URL

PTPA

Nucleotide Accession Number

NM_178001

Frequently Asked Questions

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