PTPA Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 2 phosphatase activator

Gene Aliases

PP2A, PR53, PPP2R4

Gene ID

5524

Swiss Prot

Q15257

Accession Number

NP_821068

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

AMOT; MID1; BHLHB9; SP3; STAT1; IER3; UBC; PRKCB; MAPT; EIF4EBP1; RACGAP1; APP; CAV1; AKT1; MAP2K3; MARK2; ATM; STK26; AURKB; CYLD; PPP1CA; HHV8GK18_gp81; SP1; PPP2CA; MDM2; SET; ARRB2; PIM1; PTEN; PPP2R1A; MYOCD; MYLPF; CCT5; CCT8; CCT2; CCT4; CCT7; CCT3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol