PTPA Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Protein phosphatase 2 phosphatase activator
Gene Aliases
PP2A, PR53, PPP2R4
Gene ID
5524
Swiss Prot
Q15257
Accession Number
NP_821068
Reactivity
Human
Target
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Partner Proteins
AMOT; MID1; BHLHB9; SP3; STAT1; IER3; UBC; PRKCB; MAPT; EIF4EBP1; RACGAP1; APP; CAV1; AKT1; MAP2K3; MARK2; ATM; STK26; AURKB; CYLD; PPP1CA; HHV8GK18_gp81; SP1; PPP2CA; MDM2; SET; ARRB2; PIM1; PTEN; PPP2R1A; MYOCD; MYLPF; CCT5; CCT8; CCT2; CCT4; CCT7; CCT3
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
WKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQS
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
39kDa
Protein Length
358
NCBI Gene Symbol
PTPA
Host or Source
Rabbit
Protein Name
Serine/threonine-protein phosphatase 2A activator
Gene Name URL
PTPA
Nucleotide Accession Number
NM_178001
Curated Selection
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