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PFKP Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Phosphofructokinase, platelet

Gene Aliases

PFKF, PFK-C, PFK-P, ATP-PFK

Gene ID

5214

Swiss Prot

Q01813

Accession Number

NP_002618

Reactivity

Human

Target

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11) . PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Partner Proteins

UBC; SUMO2; EGFR; rev; VAT1; TUBB4B; PPIB; PFKM; PCBP1; EEF1A1; CRYZ; HIPK4; FBXO6; MAPK4; HDAC6; SOX2; ILK; CD81; WNK1; AGO2; ITGA4; FN1; TMPO; PFKL; EPRS; COPS5; CUL3; ACD; PARD3; TINF2; FBXO25; POT1; TERF1; SIRT7; WIPI2; GBAS; DMWD; DYNLL1; MCC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

85kDa

Protein Length

784

NCBI Gene Symbol

PFKP

Host or Source

Rabbit

Protein Name

6-phosphofructokinase type C

Gene Name URL

PFKP

Nucleotide Accession Number

NM_002627

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