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VAC14 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Vac14 homolog (S. cerevisiae)

Gene Aliases

TRX, TAX1BP2, ArPIKfyve

Gene ID

55697

Swiss Prot

Q08AM6

Accession Number

NP_060522

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

The content of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns (3,5) P2. Other components of this complex are the PtdIns (3,5) P2-synthesizing enzyme PIKFYVE and the PtdIns (3,5) P2 phosphatase FIG4. VAC14 functions as an activator of PIKFYVE.

Partner Proteins

LINC00518; PIKFYVE; TCEANC; MGAT5B; C4orf33; PRR20A; PHYKPL; ACSS1; RHOXF2; PRADC1; ZNF34; LPAL2; ASB13; MTMR9; FNDC3B; NGB; SPRYD7; PELI1; PCMTD2; WDYHV1; PRR13; CD209; C11orf54; SMUG1; DDAH2; RBFOX2; SNF8; PDE4DIP; SIGLEC5; BHLHE40; TP53BP1; PPP2CA; PHF

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QLLSHRLQCVPNPELLQTEDSLKAAPKSQKADSPSIDYAELLQHFEKVQN

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 79%; Rabbit: 79%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

86kDa

Protein Length

781

NCBI Gene Symbol

VAC14

Host or Source

Rabbit

Protein Name

Protein VAC14 homolog

Gene Name URL

VAC14

Nucleotide Accession Number

NM_018052

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