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TNIP1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

TNFAIP3 interacting protein 1

Gene Aliases

VAN, NAF1, ABIN-1, nip40-1

Gene ID

10318

Swiss Prot

Q15025

Accession Number

NP_006049

Reactivity

Human, Mouse

Target

TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4 (T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.

Partner Proteins

HDDC3; MAGEB18; CFAP53; TXLNA; CCDC112; MOB3C; SYT6; TCEANC2; MOB1B; MAP1LC3A; NIFK; FAM161A; MAP1LC3B; TNIP3; SNIP1; CDIP1; NME7; MAGEH1; GABARAPL2; PNKP; MORF4L1; RALBP1; ZNHIT1; NDC80; TNIP1; OPTN; MORF4L2; AP1M1; TAX1BP1; ZBTB25; UBC; TNFAIP3; TCEA2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SPTAPACPSDKPAPVQKPPSSGTSSEFEVVTPEEQNSPESSSHANAMALG

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

70kDa

Protein Length

636

NCBI Gene Symbol

TNIP1

Host or Source

Rabbit

Protein Name

TNFAIP3-interacting protein 1

Gene Name URL

TNIP1

Nucleotide Accession Number

NM_006058

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