VPS4B Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Vacuolar protein sorting 4 homolog B (S. cerevisiae)
Gene Aliases
MIG1, SKD1, SKD1B, VPS4-2
Gene ID
9525
Swiss Prot
O75351
Accession Number
NP_004860
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Target
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
Partner Proteins
ZFYVE19; CHMP5; UBC; HTRA2; CHMP4A; TTLL12; AHCYL1; SSSCA1; YAP1; UBE4B; PDCD6IP; USP34; VPS26A; USP8; ZPR1; NUP214; TYMS; RAB5B; IGBP1; TTC9C; ZNF585B; UBQLN4; UBXN1; UBQLN1; CUL3; CHMP2A; CHMP1A; ELAVL1; BABAM1; CHMP1B; VPS4A; VPS4; LIP5
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
EKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQ
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
49kDa
Protein Length
444
NCBI Gene Symbol
VPS4B
Host or Source
Rabbit
Protein Name
Vacuolar protein sorting-associated protein 4B
Gene Name URL
VPS4B
Nucleotide Accession Number
NM_004869
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