PEX19 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Peroxisomal biogenesis factor 19
Gene Aliases
PXF, HK33, PMP1, PMPI, PXMP1, PBD12A, D1S2223E
Gene ID
5824
Swiss Prot
P40855
Accession Number
NP_002848
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Target
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Partner Proteins
FKBP7; IL23A; PEX3; UBC; PPIB; PTPLAD1; VCP; PXMP4; SLC25A17; PEX16; PEX11B; ABCD3; PMP22; EGFR; Cdkn2a; Pxmp2; TMEM54; MFSD5; PEX26; GSKIP; F11R; KIFAP3; OIP5; EIF1B; PEX11A; STK3; SRPK1; PEX14; PEX13; SMAD2; IRF3; CDC25A; NUDCD2; DSTN; NUBP2; HSPB1; PEX
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
AETPTDSETTQKARFEMVLDLMQQLQDLGHPPKELAGEMPPGLNFDLDAL
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
33kDa
Protein Length
299
NCBI Gene Symbol
PEX19
Host or Source
Rabbit
Protein Name
Peroxisomal biogenesis factor 19
Gene Name URL
PEX19
Nucleotide Accession Number
NM_002857
Curated Selection
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