MTNR1A antibody - C-terminal region (ARP61495_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Melatonin receptor 1A
Gene Aliases
MT1, MEL-1A-R
Gene ID
4543
Swiss Prot
P48039
Accession Number
NP_005949
Reactivity
Human, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep
Target
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Partner Proteins
VAPB; IRS4; RAP1A; RAC1; HSPA5; GNB1; GNAI3; GNAI2; GNAI1; GNB4; LRRC59; TMEM33; HNRNPA0; RAB10; PGRMC1; PDIA6; FLNA; EEF1G; CNP; CANX; CALR; GPR50; GNA13; DPM1; MTNR1B; MTNR1A; GNA11
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVV
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 91%; Goat: 79%; Guinea Pig: 82%; Horse: 83%; Human: 100%; Rabbit: 83%; Sheep: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
39kDa
Protein Length
350
NCBI Gene Symbol
MTNR1A
Host or Source
Rabbit
Protein Name
Melatonin receptor type 1A
Gene Name URL
MTNR1A
Nucleotide Accession Number
NM_005958
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