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DTNA Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Dystrobrevin, alpha

Gene Aliases

DTN, DRP3, DTN-A, LVNC1, D18S892E

Gene ID

1837

Swiss Prot

B4DIR0

Accession Number

NP_001185871

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast

Target

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Partner Proteins

SNTA1; ADRA1D; TJP1; ACTB; MLC1; NUP62; SEC23A; SEC24C; PSEN1; MYO1E; GFI1B; MARK2; SYNC; SNTG2; SNTG1; KCNJ12; SYNM; DTNBP1; SNTB2; SNTB1; DMD; DRP2; UTRN; ACTA1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GATTSTMRGDMVTEDADPYVQPEDENYENDSVRQLENELQMEEYLKQKLQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rat: 92%; Yeast: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

49kDa

Protein Length

452

NCBI Gene Symbol

DTNA

Host or Source

Rabbit

Protein Name

Dystrobrevin alpha Ensembl ENSP00000269192

Gene Name URL

DTNA

Nucleotide Accession Number

NM_001198942

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