DTNA antibody - C-terminal region (ARP61444_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Dystrobrevin, alpha
Gene Aliases
DTN, DRP3, DTN-A, LVNC1, D18S892E
Gene ID
1837
Swiss Prot
B4DIR0
Accession Number
NP_001185871
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast
Target
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Partner Proteins
SNTA1; ADRA1D; TJP1; ACTB; MLC1; NUP62; SEC23A; SEC24C; PSEN1; MYO1E; GFI1B; MARK2; SYNC; SNTG2; SNTG1; KCNJ12; SYNM; DTNBP1; SNTB2; SNTB1; DMD; DRP2; UTRN; ACTA1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GATTSTMRGDMVTEDADPYVQPEDENYENDSVRQLENELQMEEYLKQKLQ
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rat: 92%; Yeast: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
49kDa
Protein Length
452
NCBI Gene Symbol
DTNA
Host or Source
Rabbit
Protein Name
Dystrobrevin alpha Ensembl ENSP00000269192
Gene Name URL
DTNA
Nucleotide Accession Number
NM_001198942
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