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IRAK4 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin-1 receptor-associated kinase 4

Gene Aliases

IPD1, IMD67, REN64, IRAK-4, NY-REN-64

Gene ID

51135

Swiss Prot

Q9NWZ3-2

Accession Number

NP_001138728

Reactivity

Human, Rat, Cow, Guinea Pig, Horse, Sheep

Target

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

MYD88; IRAK1; IKBKG; SASH1; ARNT; TNFRSF13B; IL1RL1; TRAF6; PELI1; PELI2; IL1R1; MBP; HIST1H1A; HIST1H1T; HIST1H1B; HIST1H1E; HIST1H1D; HIST1H1C; EIF4EBP1; TIRAP; IRAK3; IRAK2; TLR4; TICAM2; TBPL1; PELI3; UBC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 77%; Guinea Pig: 91%; Horse: 92%; Human: 100%; Rat: 91%; Sheep: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

36kDa

Protein Length

336

NCBI Gene Symbol

IRAK4

Host or Source

Rabbit

Protein Name

Interleukin-1 receptor-associated kinase 4

Gene Name URL

IRAK4

Nucleotide Accession Number

NM_001145256

Frequently Asked Questions

More Discoveries

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