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MUS81 antibody - C-terminal region (ARP61405_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

MUS81 endonuclease homolog (S. cerevisiae)

Gene Aliases

SLX3

Gene ID

80198

Swiss Prot

Q96NY9

Accession Number

NP_079404

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig

Target

MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.

Partner Proteins

SLX4; vpr; EME1; PLK1; FBXL5; SLX1A; WEE1; EME2; SUMO2; SLX1B; MUS81; CHEK2; TERT; TERF2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GETRGGGHRPELLRELQRLHVTHTVRKLHVGDFVWVAQETNPRDPANPGE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Human: 100%; Mouse: 79%; Pig: 83%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

551

NCBI Gene Symbol

MUS81

Host or Source

Rabbit

Protein Name

Crossover junction endonuclease MUS81

Gene Name URL

MUS81

Nucleotide Accession Number

NM_025128

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