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WWOX Antibody - N-terminal region (ARP61393_P050)

Selected Variant

ARP61393_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Aliases

FOR, WOX1, DEE28, EIEE28, FRA16D, SCAR12, HHCMA56, PRO0128, SDR41C1, D16S432E

Gene ID

51741

Swiss Prot

Q9NZC7-2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human WWOX

Target

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Partner Proteins

ITCH; TRIM28; HUWE1; UBC; ATM; RPRD2; CYFIP1; SPG20; SNRNP200; ACIN1; SLC4A1AP; DHX30; SCAF8; XRN2; GABARAPL2; SEC23IP; HNRNPUL1; DIDO1; CPSF6; SF3B2; SF3A3; SRSF10; USP39; IGF2BP2; IGF2BP3; IGF2BP1; PAICS; PRPF8; CCT2; CCT7; NOP56; DDX17; SEC23A; BAIAP2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPR

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39kDa

Protein Length

363

NCBI Gene Symbol

WWOX

Host or Source

Rabbit

Gene Name URL

WWOX

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