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TNFAIP3 Antibody

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Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor necrosis factor, alpha-induced protein 3

Gene Aliases

A20, AISBL, OTUD7C, TNFA1P2

Gene ID

7128

Swiss Prot

P21580

Accession Number

NP_006281

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence LGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRP

Target

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF) . The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

Partner Proteins

YWHAQ; TNIP1; TNIP3; ARRDC3; RNF114; UBE2D1; UBC; TRAF2; TNFAIP3; TRIM23; ELAVL1; MALT1; OCLN; TP53; BIRC3; BIRC2; NFKB2; AXIN1; GIT2; IKBKG; LAPTM5; YWHAZ; YWHAE; RNF11; HSP90AA1; RNF5; RLIM; TRIM2; RBCK1; TRIM3; RNF14; TRIM5; TRIM8; TRAF6; SHARPIN; RNF3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRP

Applications

IHC

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 77%; Horse: 85%; Human: 100%; Mouse: 83%; Rabbit: 100%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

90 kDa

Protein Length

790

NCBI Gene Symbol

TNFAIP3

Host or Source

Rabbit

Protein Name

Tumor necrosis factor alpha-induced protein 3

Gene Name URL

TNFAIP3

Nucleotide Accession Number

NM_001270507

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