SFRS2 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Serine/arginine-rich splicing factor 2

Gene Aliases

SC35, PR264, SC-35, SFRS2, SFRS2A, SRp30b

Gene ID

6427

Swiss Prot

Q01130

Accession Number

NP_003007

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish

Target

The protein encoded by this gene is a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene.

Partner Proteins

KRT40; LZTS2; CEP72; HUWE1; TCF4; TRIM27; KRT31; GOLGA2; EED; PARK2; SRPK2; SRPK1; YWHAE; CIR1; UBC; U2AF1; TRA2B; SRSF4; SRSF3; SRSF2; CSNK2A1; CDK6; EIF4A3; MAGOH; PAXIP1; LIG4; ESR1; BARD1; NUBP2; UBA2; HNRNPDL; ATP6V1F; RUVBL1; XPO1; UBE2B; TTN; TPM4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

KSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

25kDa

Protein Length

221

NCBI Gene Symbol

SRSF2

Host or Source

Rabbit

Protein Name

Serine/arginine-rich splicing factor 2

Gene Name URL

SRSF2

Nucleotide Accession Number

NM_003016

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