RCC1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Regulator of chromosome condensation 1

Gene Aliases

CHC1, RCC1-I, SNHG3-RCC1

Gene ID

1104

Swiss Prot

P18754

Accession Number

NP_001260

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Partner Proteins

UBC; SUMO2; SUMO1; NEDD8; MDM2; SUZ12; RNF2; PTMA; HDAC9; HMGA1; VCAM1; ITGA4; FN1; U2AF1; RANBP1; RAN; HNRNPM; HNRNPK; LUC7L3; SF3B6; NCSTN; ACIN1; RBM14; HDGF; SPRED1; FLAD1; WIZ; LRIF1; CSAD; SDF4; TRMT2A; DDAH2; FAF1; NUDT21; CCT7; TUBB3; CDK2AP2; KMT

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKD

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

45kDa

Protein Length

421

NCBI Gene Symbol

RCC1

Host or Source

Rabbit

Protein Name

Regulator of chromosome condensation

Gene Name URL

RCC1

Nucleotide Accession Number

NM_001269

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