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IL16 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 16

Gene Aliases

LCF, NIL16, PRIL16, prIL-16

Gene ID

3603

Swiss Prot

Q8IUU6

Accession Number

AAH40272

Reactivity

Human, Rat, Guinea Pig

Target

The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

Partner Proteins

UBC; KDM1A; SUV39H1; DMRTB1; GABPB1; CSNK2A1; CDK1; HDAC3; HSPA8; USHBP1; KCNA3; PPP1R12C; KCND2; SSSCA1; EFEMP2; PPP1R12B; IL16; GRIN2D; KCNJ10; KCNJ15; PPP1R12A; KCNJ2; CASP3; KCNJ4; KCND1; CD4; GRIN2C; GRIN2A; GRIN2B; CSNK2A2; KCNJ1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DLALASEAAQLQAAGNDRGKTCRRIFFMKESSTASSREKPGKLEAQSSNF

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Guinea Pig: 100%; Human: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

50kDa

Protein Length

454

NCBI Gene Symbol

IL16

Host or Source

Rabbit

Protein Name

IL16 protein EMBL AAH40272.1

Gene Name URL

IL16

Nucleotide Accession Number

NM_001172128

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