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CUL3 Antibody - C-terminal region (ARP61263_P050)

Selected Variant

ARP61263_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Cullin 3

Gene Aliases

CUL-3, PHA2E, NEDAUS

Gene ID

8452

Swiss Prot

Q13618

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CUL3

Target

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Partner Proteins

KCTD6; ABTB1; CUL5; DEK; UBE2D1; UBC; RBX1; KEAP1; NCOA3; TNFAIP1; NEDD8; KCTD13; CUL3; SPOP; KLHL3; RHOA; ZMAT4; GMCL1; KLHL12; KCTD9; KLHL2; KLHL22; BTBD2; BTBD1; WDFY4; WDR48; LRRC7; KLHL42; WDR35; LRFN2; WDTC1; TRIM32; NLRP1; DMWD; HIRA; PHIP; PAK1IP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

84 kDa

Protein Length

768

NCBI Gene Symbol

CUL3

Host or Source

Rabbit

Protein Name

Cullin-3

Gene Name URL

CUL3

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