Hsp90aa1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Heat shock protein 90, alpha (cytosolic), class A member 1

Gene Aliases

Hs, Hsp, hsp4, 86kDa, 89kDa, Hsp89, Hsp90, Hspca, Hsp86-1, AL024080, AL024147

Gene ID

15519

Swiss Prot

P07901

Accession Number

NP_034610

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

Hsp90aa1 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Hsp90aa1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Hsp90aa1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Partner Proteins

Isg15; Akt1; Eed; Cdk4; Lrrk2; DSK2; E130012A19Rik; Fbxo32; Iqcb1; Nphp4; Chordc1; Nphp1; Ahi1; Itgb1bp2; Krt8; Nod1; Ubc; Cdc37; Traf6; Slc34a1; Slc17a1; Fkbpl

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

STMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

85kDa

Protein Length

733

NCBI Gene Symbol

HSP90AA1

Host or Source

Rabbit

Protein Name

Heat shock protein HSP 90-alpha

Gene Name URL

Hsp90aa1

Nucleotide Accession Number

NM_010480

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