CARD17 antibody - middle region (ARP61219_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Caspase recruitment domain family, member 17

Gene Aliases

INCA

Gene ID

440068

Swiss Prot

Q5XLA6

Accession Number

NP_001007233

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CARD17

Target

As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.

Partner Proteins

CARD17; CARD16; CARD18; CASP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MDKARALLDSVIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLT

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

12kDa

Protein Length

110

NCBI Gene Symbol

CARD17

Host or Source

Rabbit

Protein Name

Caspase recruitment domain-containing protein 17

Gene Name URL

CARD17

Nucleotide Accession Number

NM_001007232

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