GET4 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Golgi to ER traffic protein 4 homolog (S. cerevisiae)

Gene Aliases

CEE, TRC35, CGI-20, C7orf20

Gene ID

51608

Swiss Prot

Q7L5D6

Accession Number

NP_057033

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Target

GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.

Partner Proteins

HUWE1; PRKAB2; FAF1; VAPB; SGTA; UBC; RABEP2; LSM8; MTA2; CSTF2; FAF2; BAG6; UBL4A; VCP; EXOC2; SEC61B; TRA; AMFR; KEAP1; TMEM256; KIAA1377; ATP5H; KIFC2; EEF1G; UBAC2; SNCAIP; PLK1; PRKCSH; KAT5; TTR; PTMS; SOD2; CDKN1A; CAPNS1; WRAP73

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ASVEKGDYYEAHQMYRTLFFRYMSQSKHTEARELMYSGALLFFSHGQQNS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 93%; Rat: 93%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

36kDa

Protein Length

327

NCBI Gene Symbol

GET4

Host or Source

Rabbit

Protein Name

Golgi to ER traffic protein 4 homolog

Gene Name URL

GET4

Nucleotide Accession Number

NM_015949

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