IL2RB Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 2 receptor, beta
Gene Aliases
CD122, IMD63, IL15RB, P70-75
Gene ID
3560
Swiss Prot
P14784
Accession Number
NP_000869
Reactivity
Human, Rat, Yeast
Target
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Partner Proteins
ECM1; JAK1; SOCS3; LCK; NEDD4; HGS; UBC; EIF3B; STAT5B; SOCS1; CISH; STAT5A; IL15RA; SHC1; STAT1; IL15; SHB; JAK3; SYK; IL2RG; GNB2L1; PTPN6; PIK3R1; LYN; RAF1; IL2RA; IL2; FYN; GRB2; STAT3; JAK2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPL
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Rat: 77%; Yeast: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
58kDa
Protein Length
551
NCBI Gene Symbol
IL2RB
Host or Source
Rabbit
Protein Name
Interleukin-2 receptor subunit beta
Gene Name URL
IL2RB
Nucleotide Accession Number
NM_000878
Curated Selection
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