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IL2RB Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 2 receptor, beta

Gene Aliases

CD122, IMD63, IL15RB, P70-75

Gene ID

3560

Swiss Prot

P14784

Accession Number

NP_000869

Reactivity

Human, Rat, Yeast

Target

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Partner Proteins

ECM1; JAK1; SOCS3; LCK; NEDD4; HGS; UBC; EIF3B; STAT5B; SOCS1; CISH; STAT5A; IL15RA; SHC1; STAT1; IL15; SHB; JAK3; SYK; IL2RG; GNB2L1; PTPN6; PIK3R1; LYN; RAF1; IL2RA; IL2; FYN; GRB2; STAT3; JAK2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPL

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%; Rat: 77%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

58kDa

Protein Length

551

NCBI Gene Symbol

IL2RB

Host or Source

Rabbit

Protein Name

Interleukin-2 receptor subunit beta

Gene Name URL

IL2RB

Nucleotide Accession Number

NM_000878

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