What is the catalog number for KPNB1 Antibody - N-terminal region?

The catalog number for KPNB1 Antibody - N-terminal region is ARP61178_P050-25UL.

What sizes are available for KPNB1 Antibody - N-terminal region?

KPNB1 Antibody - N-terminal region is available in the following size(s): 25 µL.

Is KPNB1 Antibody - N-terminal region in stock?

KPNB1 Antibody - N-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

KPNB1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Karyopherin (importin) beta 1

Gene Aliases

IMB1, IPO1, IPOB, Impnb, NTF97

Gene ID

3837

Swiss Prot

Q14974

Accession Number

NP_002256

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Target

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Partner Proteins

HUWE1; UBC; FUS; SUMO2; SUMO3; STAU1; MDM2; EED; rev; CUL2; NLK; FBXO6; DYRK1B; CLK3; CDK11A; EGFR; SAMHD1; UBD; PTMA; ADRB2; RASSF5; AICDA; UBL4A; VCAM1; TAF10; NOS2; SMAD2; TAF8; TAF3; ITGA4; FN1; ERBB2; CFTR; YWHAE; SMURF1; ECT2; BARD1; MDC1; TP53BP1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol